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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-1
All Species:
6.67
Human Site:
S77
Identified Species:
12.22
UniProt:
Q99801
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99801
NP_006158.2
234
26350
S77
G
A
Q
N
D
Q
L
S
T
G
P
R
A
A
P
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
Q72
G
R
R
R
A
G
A
Q
N
D
Q
L
S
T
G
Rhesus Macaque
Macaca mulatta
XP_001106332
232
26111
S75
G
V
Q
N
D
Q
L
S
P
R
P
R
A
A
P
Dog
Lupus familis
XP_543240
206
23431
P50
S
R
P
P
H
L
E
P
P
A
A
N
Q
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P97436
237
26806
E78
G
G
R
G
V
A
P
E
D
P
P
S
I
R
H
Rat
Rattus norvegicus
P23441
372
38536
Y114
S
A
S
G
P
G
W
Y
G
A
N
P
D
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
G364
S
Q
E
W
F
E
V
G
Q
L
K
N
S
S
R
Chicken
Gallus gallus
Q90788
294
33054
P72
P
P
A
A
F
P
G
P
Y
Y
V
K
S
Y
G
Frog
Xenopus laevis
Q9W7E8
213
24704
Y57
L
R
D
T
E
E
K
Y
A
S
E
K
L
Q
S
Zebra Danio
Brachydanio rerio
Q90481
269
30288
T78
P
Y
T
R
W
L
A
T
T
D
S
I
Q
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22809
382
41975
A128
D
Y
M
Q
R
K
L
A
Y
F
G
S
T
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
P103
N
Y
F
A
G
P
F
P
G
Y
S
G
A
Q
P
Sea Urchin
Strong. purpuratus
Q26656
405
44721
T206
K
D
I
S
P
R
P
T
Q
S
H
S
S
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
91.4
58.9
N.A.
66.2
22.5
N.A.
33.7
28.2
44.4
23.7
N.A.
23.8
N.A.
25.4
25.4
Protein Similarity:
100
94
93.5
67.5
N.A.
73.4
33.5
N.A.
37.6
39.7
58.9
36.4
N.A.
37.4
N.A.
36.7
36.5
P-Site Identity:
100
6.6
80
0
N.A.
13.3
6.6
N.A.
0
0
0
6.6
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
20
80
0
N.A.
20
6.6
N.A.
33.3
13.3
20
13.3
N.A.
20
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
16
8
8
16
8
8
16
8
0
24
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
16
0
0
0
8
16
0
0
8
0
0
% D
% Glu:
0
0
8
0
8
16
8
8
0
0
8
0
0
0
0
% E
% Phe:
0
0
8
0
16
0
8
0
0
8
0
0
0
8
0
% F
% Gly:
31
8
0
16
8
16
8
8
16
8
8
8
0
0
24
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
8
0
0
0
0
8
8
0
0
0
8
16
0
0
0
% K
% Leu:
8
0
0
0
0
16
24
0
0
8
0
8
8
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
16
0
0
0
0
8
0
8
16
0
0
0
% N
% Pro:
16
8
8
8
16
16
16
24
16
8
24
8
0
8
24
% P
% Gln:
0
8
16
8
0
16
0
8
16
0
8
0
16
16
0
% Q
% Arg:
0
24
16
16
8
8
0
0
0
8
0
16
0
16
24
% R
% Ser:
24
0
8
8
0
0
0
16
0
16
16
24
31
8
16
% S
% Thr:
0
0
8
8
0
0
0
16
16
0
0
0
8
8
0
% T
% Val:
0
8
0
0
8
0
8
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
8
8
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
0
0
0
0
0
16
16
16
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _